| Tier | Definition | What it means for readers |
|---|---|---|
| Approved medicine | A regulator (FDA, EMA, or comparable) has approved the molecule in some jurisdiction | Prescription-grade evidence exists for specific indications — but off-label and compounded use are still not the approved product |
| Clinical-stage | Completed or ongoing formal human trials, without universal approval | Human safety and efficacy are being characterized; results may still fail or be withdrawn |
| Preclinical | Evidence is dominated by animal and cell-culture studies | Mechanism may be plausible; human benefit and safety are unestablished |
| Minimal evidence | Little or no formal study; claims rest on anecdote or theory | Treat all claims as unverified; risk data are absent by definition |
This table is a navigation aid into the entry pages, which carry full evidence and safety context for each compound.
Evidence tier: Approved medicine · Last reviewed: 2026-09-05 · Sources cited below.