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Approved medicineOther injectables

Teriparatide

The 1-34 fragment of parathyroid hormone, approved (Forteo) as daily injection for osteoporosis in patients at high fracture risk.

CompoundTeriparatide
CategoryApproved anabolic bone agent
ClassOther Injectables
Evidence tierApproved medicine
WADA statusNot individually listed; verify current status if subject to testing
Sold on this siteNo — this is a reference database

Overview

This entry covers Teriparatide, a approved anabolic bone agent, graded "Approved medicine" in this catalog's evidence system. This compound exists as an approved medicine in at least one major jurisdiction. Approval applies to specific, labeled indications and to the regulated product — not to compounded or research-grade copies.

The 1-34 fragment of parathyroid hormone, approved (Forteo) as daily injection for osteoporosis in patients at high fracture risk.

Mechanism of Action

Intermittent teriparatide favors bone formation over resorption — the reverse of continuous PTH exposure — rebuilding trabecular architecture.

Research and Evidence

The pivotal fracture-prevention trial (n=1,637) showed substantial vertebral and non-vertebral fracture reduction.

Evidence in context: the Other Injectables class page collects the shared evidence themes and study-reading guidance for this category.

Safety and Side Effects

Labeled cautions include hypercalcemia monitoring and a historical rodent osteosarcoma signal that restricted duration of use.

Educational notice: this entry describes published research and, where they exist, regulator labels. It is not medical advice and not a recommendation for use. Research-grade compounds have no verified human-safety data.

Frequently Asked Questions

What is the evidence tier of Teriparatide?

Teriparatide is graded "Approved medicine" on this site. This compound exists as an approved medicine in at least one major jurisdiction. Approval applies to specific, labeled indications and to the regulated product — not to compounded or research-grade copies.

Is Teriparatide an approved medicine?

Teriparatide exists as an approved medicine in at least one major jurisdiction — but approval covers the regulated product and its labeled indications only. Compounded or research-grade versions of the same molecule are not the approved product.

Where can I read the primary studies for Teriparatide?

The references section at the end of this entry links the key primary sources — regulator labels, trial registrations, and peer-reviewed papers. Our "How to Read a Peptide Study" guide explains how to evaluate them.

References

  1. DailyMed — teriparatide prescribing information. [source]
EM
Dr. Elena Marsh, PhDMolecular Pharmacology · Lead Editor

Written and maintained by the editorial team. Medically reviewed by Dr. James Okafor, MD (Internal Medicine).

Evidence tier: Approved medicine · Last reviewed: 2026-09-05 · Sources cited below.

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